Fecal Fixation: Fecal Microbiota Transplantation for Clostridium difficile Infection

Fecal microbiota transplantation for recurrent clostridium difficile infection.

With the increasing prevalence of recurrent/refractory Clostridium difficile infection (CDI), alternative treatments to the standard antibiotic therapies are being sought. One of the more controversial of such alternative treatments is fecal microbiota transplantation (FMT). Although the notion of FMT is foreign-even startling-and not esthetic to most people, the concept has been around for man...

Patient Perspectives on Fecal Microbiota Transplantation for Clostridium Difficile Infection

INTRODUCTION Clostridium difficile infection (CDI) is a severe and increasingly frequent healthcare-associated infection that develops after disruption of the gut microbiota. Immunocompromised, hospitalized patients have an increased likelihood of acquiring CDI, leading to lengthened hospital stays, increased medical fees, and higher rates of morbidity and mortality. Treatment of CDI is challen...

Lyophilized Fecal Microbiota Transplantation Capsules for Recurrent Clostridium difficile Infection

Fecal Microbiota Transplantation for Clostridium difficile Infection: The Ochsner Experience.

BACKGROUND Clostridium difficile infection (CDI) accounts for 20%-30% of cases of antibiotic-associated diarrhea and is the most commonly recognized cause of infectious diarrhea in healthcare settings. The incidence of CDI is rising, while the effectiveness of antibiotics for treatment decreases with recurrent episodes. The use of fecal microbiota transplantation (FMT) for cure of CDI has been ...

Fecal Microbiota Transplantation for Clostridium difficile Infection: A Systematic Review.

BACKGROUND The role of fecal microbiota transplantation (FMT) for Clostridium difficile infection (CDI) is not well-known. PURPOSE To assess the efficacy, comparative effectiveness, and harms of FMT for CDI. DATA SOURCES MEDLINE (1980 to January 2015), Cochrane Library, and ClinicalTrials.gov, followed by hand-searching references from systematic reviews and identified studies. STUDY SELE...